They had such a sharp disagreement that they parted company. Barnabas took Mark and sailed for Cyprus, but Paul chose Silas and left, commended by the believers to the grace of the Lord.

Acts 15

They had such a sharp disagreement that they parted company. Barnabas took Mark and sailed for Cyprus, but Paul chose Silas and left, commended by the believers to the grace of the Lord. v39-40

Although Barnabas and Paul had a sharp disagreement, it did not stop them from moving forward with their mission to spread the good news of Jesus Christ. Eventually, Barnabas and Paul reconcile - see 1 Corinthians 9:6.*  Another lesson* to be gleaned here is that believers should submit to those in higher authority in the church.

This is consistent with scripture elsewhere: 

Slaves, in reverent fear of God submit yourselves to your masters, not only to those who are good and considerate, but also to those who are harsh. 1 Peter 2:18

My Prayer: Lord, You are a great God and You have provided many people in my life that have led me, coached me, pastored to me, mentored me, etc.  I know You have put these people in my life.  I am deeply grateful for Your guidance through these people Jesus.  Yet sometimes I am not grateful and I reject Your guidance.  I am sorry Lord.  Help me overcome such sin and turn from such sin towards You.  Help me love You with all of my heart, soul, mind, and strength.  Help me love others as You do.  Help me grow in my faith.  Help me understand Your message for me today.  Help me be obedient and apply this message.

*MacArthur, John (2005-05-10). The MacArthur Bible Commentary (Kindle Locations 48518-48520). Thomas Nelson. Kindle Edition.